Why it would be nice to experience some side effects after the Covid vaccine

Although the malaise after vaccination is usually uncommon and subsides after a day or two, some hospitals and medical centers offer the amazing vaccine to health workers for a short collection of avoidance of absence.

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1. What ideas can happen?

Typical symptoms include a sore arm, usually localized to the area where the vaccine was given, and systemic symptoms, such as a mild fever or elevated temperature, headache and muscle aches. Some studies have found that younger adults report local and systemic reactions more often than those over 65 years of age. A type of skin rash, called a morbilliform rash, was reported in a 30-year-old male health care worker two days after his second injection. The broth, which covered most of his back, resolved after a day.

2. Are they a cause for concern?

Reactions can be unpleasant, but they are usually short-lived and far more dangerous than those caused by a natural infection. Vaccines are extensively tested for safety before release. Once used on a large scale, they are closely monitored in “post-market” monitoring systems for unexpected or rarely unusual reactions. build-up in clinical trials. Although side effects from vaccines are not uncommon, these products would not be tolerated if they were likely to be severe or permanent.

3. What causes a reaction to vaccines?

Vaccines are designed to recognize a natural disease without the full-blown disease, thus generating immunity. Reactions are usually the result of the immune system’s response to the main component: an antigen that is similar to whatever it is designed to fight.

Usually, when the body is exposed to bacteria, viruses or other potential enemies, immune defenses try to neutralize and destroy it. Chemicals that attract cells to kill the invader have been released in a process that could raise body temperature, said Peter English, a UK consultant in infectious disease control and a former at the journal Vaccines in Practice.

A large army of T cells and B cells is recruited called the enemy’s permanent “memory” and how to stop it. “In learning to recognize the pathogen, the body passes through the same protective reactions as it would have if it had met the patty for real, eliciting many of the same reactions, “English said.

4. What else can cause a reaction?

Vaccines may also contain components that stimulate a reaction, or that enhance the immune response to vaccine antigens, English said. Covid-19 vaccines can also be:

Preserve to prevent the vaccine from spoiling.

Microscopic bubbles of lipids or fat products containing the genetic material for mRNA vaccines (manufactured by Moderna Inc., Pfizer Inc. and BioNTech SE) to direct cells to produce SARS-CoV-2 antigens.

Harmless viruses to introduce genetic material into the cells to direct them to produce SARS-CoV-2 antigens.

Chemical “chemical adjuvants” designed to increase the immune response to the antigens.

5. Why are opinions about the second dose worse?

It takes some time for the immune system to reverse its response to a new pathogen. Immune memory cells are programmed so when they encounter a second attacker – either from a natural infection or vaccine antigens – they are expected to respond faster and stronger. This recognition usually triggers a mass production of immune signaling molecules or “cytokines” that are responsible for muscle pain, fever, chills and sometimes fat burners. The upside is that the second occurrence acts as a boost that should make for a more robust, lasting immune response.

6. What is it like for Covid-19 survivors?

Their reaction to the picture may be more pronounced, but the benefits are likely to be just as great. Florian Krammer and colleagues at the Icahn School of Medicine at Mount Sinai in New York compared the effects of mRNA vaccines on people with and without previous antibodies to the coronavirus.

The researchers found that antibody levels of those with preexisting immunity were 10 to 45 times as high as those without at the same points in time after the first vaccine dose. Local reactions to the vaccine occurred at the same rate in all groups at the time of vaccination and were resolved independently days later.

However, systemic side effects – such as fatigue, headache, cold, fever and muscle aches – occurred after vaccination in 89% of those with preexisting immunity, compared with 46% of vaccines without.

7. Is feeling lousy after vaccination a good sign?

It’s encouraging to think that it is – and perhaps it is, English said, although “I’m not sure there is a wealth of data that proves it.” At the very least, mild, short-term fever indicates that the immune system is responding in a way that should provide protection against the coronavirus if it actually occurs.

8. Can you take something for it?

A low fever of about 38.5 degrees Celsius (101 degrees Fahrenheit) is part of the body’s normal response to disease and is not harmful. If acceptable, rest and fluids are the best cure, according to English. Constant temperatures above 39 degrees Celsius are more dangerous, especially in infants. Taking aspirin, acetaminophen / paracetamol (such as Tylenol), or a non-steroidal anti-inflammatory drug such as ibuprofen to relieve pain and fever is unlikely to adversely affect the quality of the immune response.

This story was published from a wire group group with no text changes.

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