- A pair of new coronavirus vaccine studies show that a single dose triggers a strong immune response in survivors of COVID-19, suggesting that authorities should consider changing protocol for people at risk. had the illness.
- One study showed that one vaccine picture is enough to increase the number of antibodies by a thousand times, to a level that would neutralize the mutation of South Africa and even the SARS virus from 2013.
- A separate study confirmed the same strong immune response in COVID-19 survivors after just one picture.
- In early February, two other studies also showed that COVID-19 survivors develop a strong immune response after a single dose of vaccine, indicating that a change in vaccine protocol may be required.
The number of new COVID-19 cases has been falling sharply in the last few weeks. However, hundreds of thousands of people are still being diagnosed every day, and tens of thousands are still dying every day from coronavirus complications. Vaccination campaigns have reached a notable milestone, with more than 200 million people receiving at least one dose of vaccine to date. More than 35.7 million people have completed the two-dose program. Despite these developments, the pandemic remains a worldwide concern, especially considering the large mutations discovered in late 2020 and early 2021. The novel coronavirus is come through genetic changes just like any other infectious microorganism, and some of the new mutants are more resistant to vaccines. Further wave fuel variations and further delay could delay the spread of the pandemic, especially if these genetic changes can avoid immunization.
Recent developments from Pfizer and BioNTech will allow both companies to ramp up vaccine supply. Their vaccine can be stored at higher temperatures, which may expand the reach of vaccine enterprises. In addition, drugs such as Johnson & Johnson ‘s candidate could soon be licensed for emergency use, increasing the number of vaccine candidates that can prevent heavy COVID-19. But there may be further development now that will increase vaccine access. New studies show that coronavirus vaccination protocols may require a major change that would give more people more vaccines.
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In early February, four coronavirus studies came out to address various aspects of COVID-19 immunity. One said that immunity after an infection lasts at least six months after the first infection. A separate study showed that COVID-19 remodeling may be more common than we expected, but relapse is likely to lead to asymptomatic cases of COVID-19. Two other teams independently concluded that a second dose of vaccine is not necessary in survivors of COVID-19. Researchers from the Icahn School of Medicine and scientists from the University of Maryland in Baltimore confirmed that a single dose of vaccine would elicit a strong immune response in survivors, proposing a new strategy for vaccinating survivors already in COVID-19.
Since then, two new studies have come out and reached the same conclusions. People who survive the infection will receive a strong immune response after a single dose of vaccine.
The first study comes from the Fred Hutchinson Cancer Research Center in Seattle. Researchers looked at blood samples from survivors and found that the existing antibodies would have a harder time neutralizing B.1.351 mutations that appeared in South Africa. This is in line with recent research that suggested that survivors of COVID-19 may be re-exposed to South African snoring. But the good news far outweighed the bad.
The researchers vaccinated the volunteers with one vaccine from Pfizer / BioNTech or Moderna. This caused an increase of antibodies in their blood by a thousand miles, The New York Times reports. Psychologist Andrew T. McGuire told the paper that this was a “huge, huge stimulus” of the immune system.
More interestingly, blood samples taken two or three weeks after vaccination showed that all participants could neutralize the B.1.351 strain. Moreover, the antibodies could even neutralize the SARS virus that caused the 2003 infection. The Times noting that the antibodies appeared to perform better than they do in people who did not have COVID-19 and received two doses of vaccine.
“It seems very clear that we are strengthening their previous immunity,” said McGuire. The researchers also saw an increase in immune cells that remember and fight the virus.
Separately, scientists from New York University found that a second dose of the vaccine did not improve the immune response in COVID-19 survivors compared to just one picture. The authors looked at people who received the vaccine eight or nine months after becoming infected with COVID-19. The number of antibodies increased by between one hundred and one thousand times after the first dose. But they did not rise again after the second dose.
“It is a testament to the strength of immunologic memory that they receive a single dose and have a significant increase,” said NYU Langone Vaccine Center director Dr. Mark J. Mulligan The Times. He said those who survived COVID-19 “should definitely be vaccinated. ”
Although both new studies have been published without peer review, they confirm results from previous research. These findings could lead to ongoing changes to vaccine protocols. On Saturday morning, more than 111 million people have been diagnosed with COVID-19 worldwide since trials began, with more than 2.47 million people dead. Several studies have shown that the true number of COVID-19 infections appears to be significantly higher, as many people have never been diagnosed. A live vaccine with just one dose could free up hundreds of millions of doses and have a major impact on the routine distribution of vaccines.
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Chris Smith began writing about gadgets as a hobby, and before he knew it he shared his views on tech stuff with readers around the world. When he’s not writing about tools he finds it hard to stay away from them, even though he’s trying hard. But that is not necessarily a bad thing.