Scientists at the RIKEN Center for Biosystems Dynamics Research in Japan led by Takashi Tsuji have been working on ways to lose hair from cells. And they may just have made significant progress!
In mammals, hair grows in a continuous circular process that sees hair grow, fall out, and grow back. Therefore, successful hair restoration treatment would have to result in hair that also regenerates itself.
To test whether stem cells from fur and whiskey from mice cultured in the middle of NFFSE (a type of five-factor collagen) could remove circulating hair, the loader looked -research the hair restoration for several weeks. They also used 220 mixtures of ingredients.
The experts found that 81% of hair follicles created in the middle of NFFSE went through at least three hair cycles and removed normal hair while 79% of follicles that went through growth in the other medium produces only one hair circle.
The researchers also saw what is attached to the outside of the cells. They found that the best hair cycling was associated with the addition of Itgβ5.
“We found that nearly 80% of follicles reached three hair follicles when Itgβ5 was introduced into the hair organism,” he explained in a statement by first author Makoto Takeo. “On the other hand, only 13% reached three rounds in absence.” The analysis showed that these important cells are located naturally in the upper part of the bulge area of the hair follicle.
“Our culture system is establishing a method for the cyclical regeneration of hair follicles from hair follicle cells,” says Tsuji, “and will help make hair follicle regeneration therapy possible soon. ”
The next step in the process is now clinical trials with humans. If the research is successful in these trials, this process could one day turn into a commercially available baldness treatment.