News – People with severe COVID-19 and secondary blood disease were severely ill when they were admitted to hospital, had longer hospital stays and worse outcomes, according to the Rutgers study.
The study, published in the journal Clinical infectious diseases, the first to evaluate microbiology, risk factors, and outcomes in hospitalized patients with severe COVID-19 infections and secondary blood flow.
The researchers looked at 375 patients diagnosed with severe COVID-19 between March and May 2020. Of that group, they sampled 128 cases with secondary bloodstream infections, 92 percent of which of bacterial infections.
“These patients were more likely to have a change in mental status, lower percentage oxygen absorption, septic shock and be admitted to the intensive care unit compared to those without bloodstream infections,” said co-author Pinki Bhatt, assistant professor at Robert Rutgers Wood Johnson School of Medicine Department of Allergy, Immunology and Infectious Disease.
The researchers also found that patients who needed more advanced types of extra oxygen when they were admitted to hospital had higher rates of secondary blood flow diseases.
The in-hospital mortality rate for these patients was more than 50 percent, but the study revealed that these deaths were related to it, and not the condition with the condition.
According to the study, infections in COVID-19 patients may have contributed to the severity of the disease or may indicate other physiological and immunological complications of COVID-19.
The study showed that the most common cause of secondary bloodstream diseases was not known or confirmed and then with midline-related bloodstream disease as the most common source.
The study found that 80 percent of all patients in the study received non-chemical substances at some point in the hospital, including those who did not have bloodstream infections. “This tends to reflect the tendency of clinicians to administer non-chemical substances due to the lack of information on the natural course of this novel disease,” Bhatt said. She noted that further studies are needed to better understand when to suspect and empirically treat secondary secondary blood flow infections in severe COVID-19.
Other Rutgers authors include Stephanie Shiau, Luigi Brunetti, Yingda Xie, Kinjal Solanki, Shaza Khalid, Sana Mohayya, Pak Ho Au, Christopher Pham, Priyanka Uprety and Ronald Nahass.