Researchers with the Fatty Acid Research Institute (FARI) and colleagues at Cedars-Sinai Medical Center in Los Angeles and Orange County, CA, have published the first direct evidence that blood levels of omega-3 may increase reduce the risk of death from COVID-19. infection. The report was published in the journal Prostaglandins, Leukotrienes and essential fatty acids on January 20, 2021.
Several papers in the medical literature consider that omega-3 fatty acids should have beneficial effects in patients with COVID-19 infection, but to date, peer-reviewed studies have not been published. support that view.
This study included 100 patients admitted to the hospital with COVID-19 where invasive blood samples were stored. Clinical results for these patients were obtained and blood was tested for OmegaQuant Analytics (Sioux Falls, SD) Omega-3 (O3I, EPA + DHA red blood cell levels). Fourteen of the patients died.
The 100 patients were placed in four quarters according to their O3I, with 25% of patients in each quarter. One death was in the top quartile (i.e., 1 death out of 25 patients with O3I> 5.7%), with 13 deaths in the remaining patients (i.e., 13 deaths out of 75 patients and O3I
In age and gender-adjusted regression analyzes, those in the top quartile (O3I> 5.7%) were 75% more likely to die compared to those in the bottom three quarters (p = 0.07). In other words, the risk of death for death was about four times higher in those with lower O3I (
“Although they do not meet the usual statistical thresholds, this pilot study – along with several lines of evidence regarding the anti-inflammatory effects of EPA and DHA – strongly suggests that these available marine fatty acids may be access to nutrition helps reduce the risk for adverse outcomes in COVID-19 patients. It is clear that larger studies are needed to confirm these initial conclusions, “said Arash Asher, MD, lead author of this study.
Agreeing with Dr. Asher, a cartography researcher and co-developer with Dr. Harris of the Omega-3 Index, said Clemens von Schacky, MD, (CEO, Omegametrix GmbH, Martinsried, Germany, and not involved in the study), “Asher has et al confirmed that Omega Index could -3 low may be a powerful predictor of death from COVID-19. While encouraging, it is clear that their results need to be replicated. “
Omega-3 expert James H. O’Keefe, Jr., MD, (Director of Preventive Psychology, Saint Luke’s Central American Heart Institute, Kansas City, MO, and also not involved in the study), noted “An inflammatory response extreme, “referred to as ‘storm cytokine,’ a primary mediator of COVID-19 disease. Omega-3 fatty acids (DHA and EPA) have strong anti-inflammatory activities, and this pilot study provides evidence that these fatty acids may be harmful. Storm cytokine COVID-19. ”
The FARI research team is currently seeking funding to expand on these preconceptions. Individuals and organizations wishing to support this research are encouraged to visit the FARI grants page.
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Media Queries:
Bill Harris,
President, FARI
Email: [email protected]
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About the Fatty Acid Research Institute (FARI)
The Fatty Acid Research Institute (FARI) is a nonprofit research and education foundation. FARI was established to determine the health effects of fatty acids, in particular, the long-chain omega-3 fatty acids EPA and DHA. FARI researchers and scientists focus individually on publishing high-quality research studies on the multiple relationships between fatty acid levels and human (and animal) health outcomes. These studies will improve the ability to predict risk for disease, and more importantly, suggest ways to reduce risk by changing our diet and / or developmental regimens.
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About Cedars-Sinai Medical Center
Cedars-Sinai is a nonprofit academic healthcare organization that serves the diverse community of Los Angeles and beyond. With advanced medical research achievements, educational programs outlining the future of health care, and broad community welfare activities, Cedars-Sinai sets new standards for quality and innovation in patient care.
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