Protection against recurrence of SARS-CoV-2 infection by about 80 percent

(HealthDay) – Protection against infectious respiratory coronavirus syndrome 2 (SARS-CoV-2) is about 80 percent but lower among older people, according to a study published online March 17 in The Lancet.

Christian Holm Hansen, Ph.D., of the State Serum Institut in Copenhagen, Denmark, and colleagues collected data on patients diagnosed in Denmark in 2020 and analyzed infection rates during the second increase of COVID-19 infection, from September. . 1 to December 31, 2020. Infection rates were compared for individuals with positive and negative test results during the first increase (March to May 2020). In another cohort study, infection rates were compared during the year between those with and without previously diagnosed disease at least three months earlier, regardless of date.

The researchers found that, among advanced individuals from the first outbreak of the disease, 0.65 percent tested positive again during the second increase compared to 3.27 percent who tested negative during the first outbreak (altered rate ratio , 0.195), resulting in an 80.5 percent defense against repetition. infection. Similar estimates were seen in the other cohort analysis (adjusted rate ratio, 0.212; estimated protection, 78.8 percent). In the other cohort analysis, protection against recurrent infections was 47.1 percent among those aged 65 years and older. No difference in relapse was observed by sex, and there was no evidence that immunity declined over time.

“Our data show that vaccination of previously infectious people should be carried out as natural protection cannot be relied upon,” the authors write.

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