Of course, the team wanted to see if those results were translating to people, and a long story short, they did.
When common food antigens were administered to IBS patients intravenously (gluten, soy, cow’s milk, etc.), the researchers observed the same local immune response as they did in the mice. It is also worth noting that the research team had previously completed research that found that histamine inhibition improved symptoms for people with IBS.
To date, these food intolerances have not been well understood, as they are not perceived as a normal food allergy. As a gastroenterologist and lead author of the study, Guy Boeckxstaens Ph.D. explains in a press release, “At one end of the spectrum, the immune response to food antigen is highly localized, as in IBS. At the other end of the spectrum is food allergy, including a general state of activation. hard mast cells, affecting respiration, blood pressure and so on. “