A new study led by Ohio State University suggests that electrical stimulation may enable blood vessels to carry white blood cells and oxygen to wounds, speeding up the healing process. The study, published in the journal Royal Society of Chemistry Lab on a Chip, found that sustained electrical stimulation generates increased permeability across blood vessels, giving us new insights into the ways in which new blood vessels can grow.
The electrical stimulus provided a constant voltage with accompanying electric current in the presence of water flow. The findings show that stimulation increases blood vessel regeneration – an important feature that helps wound healing products in the blood reach more effective wounds. “There was this profiteering that blood vessels could improve if you stimulated them electronically,” said Shaurya Prakash, lead author of the study and associate professor of mechanical and aerospace engineering at Ohio State University. “And we found that the response of the cells in our blood vessel models shows great promise towards the remodeling of the vessels which may yield good results for our ongoing work there. the healing of wounds. “
Blood vessels are essential for wound healing: They thread throughout your body, carrying nutrients, cells and chemicals that help control inflammation that causes injuries. Oxygen and white blood cells – which protect the body from foreign invaders – are two key components delivered by blood vessels. But when there is an injury – for example, a cut on your finger – the architecture of the blood vessels at the site of the injury is disturbed. That also impairs the ability of the vessels to heal the injury. Blood vessels regenerate on their own, almost like tree branches, without external electrical sources, as part of the healing process.
“And as the blood vessels begin to grow, they replenish the skin and cells and re-establish a healing barrier,” Prakash said. “But our question was: How can you make this process better and faster, and is there any benefit in doing that?” Their findings are that, in laboratory experiments performed using human cells, the stimulation of blood by electricity showed a significant increase in blood vessel regeneration, which is a physical symptom that reveal the growth of a potential new vessel.
“The first results are interesting, and the next phase of the work needs to explore how and how we can grow new vessels,” said Prakash. mechanical and aerospace engineering at Ohio State, that the findings make it one of the main ways blood vessels work to heal injuries by allowing molecules and cells to move over the vessels’ walls.
“And now we have a better understanding of how electrical stimulation can alter the resilience across the walls of the vessel,” Song said. “We say you have a skeletal injury, like a paper cut, and the Your blood vessels are separated and that is why blood is leaking. All you need is a handful of blood cells that come to that place and go out of the blood vessel to apply for the repair of the wound. “The study suggested that changes in blood pollution could bring these blood cells to the site of injury more quickly, although it did not explain the reasons for what happened. The study appeared to indicate that electricity affects the proteins that hold blood cells together, but these results were uncertain.
The study is an extension of work with a broader team, led by Prakash, who previously showed that electric bands could help promote healing in injured dogs. That work showed that electrical stimulation could help control disease at injury sites – something the researchers hope to do more research on. (ANI)
(This story was not edited by Devdiscourse staff and is automatically extracted from syndicated feedings.)