‘Covid vax must prevent disease, progression and transmission’

LONDON: To make the global Covid-19 vaccine program a success, the available vaccines need to be able to do all three – prevent the establishment of disease in an individual, prevent the progression of disease and prevent spread, say researchers.
“It is not known whether all three of these goals will be achieved with ‘first generation’ vaccines, but it is crucial for the long-term success of the program,” he said. study published in the journal Anesthesia.
“Preventing proliferation – referred to as ‘sterilizing immunity’ – is particularly important because of its epidemic change,” said the influential committee of the Scientific Advisory Group for Emergencies (SAGE).
“It is possible that the first vaccines, including those that are now being released, may be more effective in preventing the progression of disease and hospitalization and may not be as effective. effective in preventing spread, “he explained study senior author Jeremy Farrar of SAGE.
“Knowledge of performance in pre-licensing and post-licensing testing will allow further changes so that second- and third-generation improved vaccines will be available later in 2021 and beyond,” Farrar said. .
They also stress the importance of prioritizing the most vulnerable workers and health care before the general population.
The authors said, “Vaccination is a global thing rather than a national requirement.”
The acceleration of ACT by the World Health Organization (WHO) and COVAX initiatives both emphasize the importance of vaccines reaching the most vulnerable workers and health care in all countries at the same time. .
A comprehensive vaccination of one or a few countries without addressing this need worldwide is not in the best interests of anyone and will not provide the protection we all need.
“No country has launched a population vaccination campaign as a living reminder, and it must be undertaken with local leadership and cultural sensitivity,” the experts stressed.
They also discussed the effects of widespread vaccination and the challenges for those who do not receive the vaccine.
They asked: “Will a vaccination certificate (vaccine permit) be a requirement for patients and their families before elective surgery, or working in health or social care, traveling abroad, or attending conferences? medical, or even take part in the Olympics?
The authors make it clear that the vaccine is not a panacea, and that SARS-CoV-2 will not be brought under full control by continuing to change our behavior, as well as improve accessibility. on diagnosis and treatments, but add: “safe and effective vaccines will undoubtedly change the course of the pandemic, rebuild confidence and begin to return to the ‘pre-Covid’ era. ”
“There is no merit or safety in creating high levels of vaccination and low levels of disease within the borders of one country if this is not reproduced throughout the rest of the world. We are all here together, “they concluded.