Antibodies against coronavirus may not work against a variety of new viruses identified in South Africa, a recent study said. The scientists had previously stated that the 501.V2 variable virus has developed a number of mutations in the spike protein, the latter of which binds to human cells and absorbs them. So, vaccines and antibodies. targeting the spike protein may not work on the new virus.
Now, a new study, published in the bioRxiv preprinted database, suggests new evidence for the case. The study, which was not peer-reviewed, found that specific mutations in the spike protein make the variant more vulnerable to some people’s antibodies, however, these mutations do not the incredible new variant, just more vulnerable to attack. The study also said that some people’s antibodies were still able to bind well to the mutant and in that case, anti-COVID drugs may work.
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“Unfortunately, the E484 site has a 501.V2 mutation, as do some other locations from elsewhere. That means the variant may be as vulnerable to some people’s antibodies as to antibody drugs, but more studies are needed to see if this affects vaccine-generated antibodies, ”said the report. -authorities.
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What is known about the COVID-19 variant in South Africa?
However, mutations at one point on a spike protein called E484 emerged as a potential cause. According to researchers, a mutation at this level caused a decrease in the ability of antibodies to prevent the virus from entering cells larger than 10-fold. Even though South African experts are still looking into the details of the new COVID-19 modification, the health minister said last week that the particular pressure had affected the results of the diseases, especially in the last two months. Calling it a trend in the epidemiological scene, doctors have reported that co-infections affected more younger patients and developed severe forms of the sometimes fatal infectious disease.
South Africa’s health minister has also revealed that elements related to the new coronavirus mast “strongly indicate” that the second wave in the country is “carried” by the new version because the strain new in nearly 90% of the samples tested in the country. . As reported, unlike other mutations that die off, the 501.V2 has significantly altered the part of the pathogen that helps maintain adherence to host cells in humans. It is also the only part of the virus that is affected by the vaccines and antibody treatments.