An integrated approach to effective prevention of Alzheimer’s disease

Amsterdam, 29 December 2020 – This groundbreaking new study by Prof. Ricardo Maccioni and cooks of the International Center for Biomedicine, “New Frontiers in the Prevention, Diagnosis and Treatment of Alzheimer’s Disease” published in the special issue of Latin America. inspectors of the Journal of Alzheimer’s disease(JAD). This supports a growing research group on the value of Alzheimer’s prevention of an integrated approach using daily exercise, nutraceuticals, coastal practices such as QiGong along with meditation, and social life. These elements of a healthy lifestyle are augmented by the use of reliable biomarkers for early detection of this disease that allow the detection of Alzheimer’s up to 20 years before the symbolic stage of the disease.

Alzheimer’s disease (AD) is one of the leading puzzles in medical research and public health systems worldwide, reaching a level of nearly 50 million people today. AD is a multifactorial brain disorder characterized by progressive brain impairment, apathy, and mood disorders. The main risk of AD is aging. Studies suggest that AD is a breakdown from aging with changes in the powerful functional capabilities of neurons as well as in neuronal immune mechanisms. There are factors that determine the loss of function during age, an important role is played by epigenetic components. Thus, the function of AD-susceptible genes can be mitigated by healthy lifestyles, physical exercise, balanced nutrition, avoiding molecules that are harmful to health and drugs. Active social life and active activity in the last years of growing older, to achieve health at an advanced age.

In this context, an important pathway to AD inhibition was opened considering the factors mentioned above and control of neuroinflammatoy events (Figure 1). On the basis of medical evidence we conclude that a reasonable integration of all these factors leading to a protective action against neuronal degeneration in AD leads to a better quality of life. Further prevention of innovative screening programs for early detection of the disease using reliable biomarkers is becoming essential for controlling the disease. Our own data suggest that AD is a clear break with normal age; understands that this process requires a system of biology-based approach. Moreover, the failure of traditional pharmaceutical therapies and the discovery of new drugs have stimulated the promotion of nutraceutical compounds in the context of “multitarget” medicine, as well as non-pharmacological approaches that have been used. shown to be effective in aging, and applied in AD control. An integrated approach that incorporates all of these protective factors along with new multi-guitar therapeutic approaches should pave the way for future disease control.

###