Below you will find summaries of new articles to be published in the next issue of History of internal treatments. The abstracts are not intended to replace the complete articles as a source of information. This information is subject to a strict embargo and by including it, the media representatives promise the terms of the embargo not only on their own behalf, but also on behalf of the organization they represent.
1. Adherence to a low dose aspirin regimen resulted in improved pregnancy outcomes in women with previous pregnancy loss
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Adherence to a low-dose aspirin regimen resulted in improved pregnancy outcomes in women with previous pregnancy loss who were trying to conceive. The beneficial effect of aspirin was stronger if women started taking it before pregnancy and became weaker if they started taking it after the 6th week of pregnancy. This analysis of each protocol of a randomized controlled trial is published in History of internal treatments.
In the EAGeR (Effects of Aspirin in Gestation and Reproduction) trial, researchers examined the effects of low-dose aspirin treatment initiated by a prediction of pregnancy loss and live birth in 1,227 women trying to conceive a child after 1 or 2 pregnancy loss. The lawsuit found that women who were prescribed to take low-dose aspirin daily doses before pregnancy did not have pregnant products. However, many of the patients in the trial did not adhere strictly to the aspirin protocol, which was not included with the originally published intentional treatment approach.
Researchers from Emory University and the National Institutes of Health used data from the EAGeR test to conduct a post hoc study for each protocol to see if almost daily aspirin would increase pregnancy or reduce pregnancy loss . The researchers compared the chances of pregnancy, loss of pregnancy, and live birth that would have occurred under high levels of aspirin versus placebo.
The analysis of each protocol showed that adherence to low-dose aspirin treatment for at least 5 of 7 days a week resulted in 8 more pregnancies, 6 fewer weight loss, and ultimately 15 more live births. for every 100 women in the test. According to the authors these findings suggest that efforts aimed at improving daily compliance with low-dose aspirin may improve the effectiveness of aspirin on reproductive outcomes for women who are pregnant. trying to give birth.
Media contacts: For an embargoed PDF, contact Lauren Evans at [email protected]. Corresponding author, Ashley I. Naimi, PhD, can be reached through Robert Bock at [email protected].
Also in this issue:
The feelings about getting the COVID-19 vaccine
Grace Farris, MD
Graphic treatment
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