Addressing the biological causes of racial differences in prostate cancer

African Americans have higher rates of prostate cancer and are more likely to die from the disease than other groups in the United States, possibly due to socioeconomic factors, health care access problems, and tumor biology. New review published in Cancer reports focusing on the biological differences in prostate cancer development across races.

The authors note that these differences may be reduced to the diagnosis and treatment of prostate cancer in African American men, ultimately reducing the incidence and mortality rates of co-morbidities. -connected with the disease.

“We provide a comprehensive review of the important research in recent years that has examined the molecular and genomic causes of unequal cancer burden in African American and Caucasian American populations and recognizes the challenge ahead, “said lead author Ashutosh K. Tewari, MD, of the Icahn School of Medicine at Mount Sinai.” This article provides specific guidelines for the management of prostate cancer in African American men. on the biology of their disease and contribute significantly to the ongoing national effort to improve the outcomes of African American men from prostate cancer. “

“Understanding the specific biology of prostate cancer in African American men and integrating clinical and genomic data will allow and enhance a ‘precision treatment’ approach to the treatment of African American men. the ongoing efforts to improve outcomes in this population, ”said co – author Sujit S. Nair, PhD.

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