WASHINGTON: Researchers have now reported that more and more evidence is emerging that people with Covid-19 suffer from cognitive effects, such as brain fog and obesity.
The study, published in the journal Nature Neuroscience, found that the spike protein, often seen as the red arm of the virus, can cross the blood-brain barrier in mice.
This strongly suggests that SARS-CoV-2, the cause of Covid-19, can enter the brain.
“The spike protein, often called the S1 protein, determines which cells the virus can enter in. The virus usually does the same thing as its binding protein. , “said lead author William A Banks of Washington University in the USA.
Banks said binding proteins such as S1 alone usually cause damage as they separate from the virus and cause inflammation.
“The S1 protein appears to cause the brain to release cytokines and produce inflammatory products,” he said.
In science circles, the severe inflammation caused by Covid-19 infection is called cytokine storm.
The immune system, when it sees the virus and its proteins, overwhelms its attempt to kill the invading virus. The infected person is left with brain fog, fatigue and other mental issues.
The research team saw this reaction with the HIV virus and wanted to see if the same thing happened with SARS CoV-2.
Banks reported that the S1 protein in SARS-CoV2 and the 120 gp protein in HIV-1 work in the same way.
They are glycoproteins – proteins that are high in sugar, signaling proteins that bind to other receptors.
Both of these proteins act as arm and arm for their viruses by attaching to other receptors. Both cross the blood-brain barrier and S1, like gp120, is likely toxic to brain tumors.
“It was like deja vu,” said Banks, who has done a lot of work on HIV-1, gp120, and the blood-brain barrier.
Banks lab examines blood-brain barrier in Alzheimer’s, obesity, diabetes and HIV. But they suspended their work and all 15 people in the lab began their S1 protein tests in April.
The study they could explain many of the problems from Covid-19. Raber stated in their experiments that transport of S1 was faster in the olfactory bulb and kidney of males than females.
This observation may be related to increased male vulnerability to more robust Covid-19 products.
The study, published in the journal Nature Neuroscience, found that the spike protein, often seen as the red arm of the virus, can cross the blood-brain barrier in mice.
This strongly suggests that SARS-CoV-2, the cause of Covid-19, can enter the brain.
“The spike protein, often called the S1 protein, determines which cells the virus can enter in. The virus usually does the same thing as its binding protein. , “said lead author William A Banks of Washington University in the USA.
Banks said binding proteins such as S1 alone usually cause damage as they separate from the virus and cause inflammation.
“The S1 protein appears to cause the brain to release cytokines and produce inflammatory products,” he said.
In science circles, the severe inflammation caused by Covid-19 infection is called cytokine storm.
The immune system, when it sees the virus and its proteins, overwhelms its attempt to kill the invading virus. The infected person is left with brain fog, fatigue and other mental issues.
The research team saw this reaction with the HIV virus and wanted to see if the same thing happened with SARS CoV-2.
Banks reported that the S1 protein in SARS-CoV2 and the 120 gp protein in HIV-1 work in the same way.
They are glycoproteins – proteins that are high in sugar, signaling proteins that bind to other receptors.
Both of these proteins act as arm and arm for their viruses by attaching to other receptors. Both cross the blood-brain barrier and S1, like gp120, is likely toxic to brain tumors.
“It was like deja vu,” said Banks, who has done a lot of work on HIV-1, gp120, and the blood-brain barrier.
Banks lab examines blood-brain barrier in Alzheimer’s, obesity, diabetes and HIV. But they suspended their work and all 15 people in the lab began their S1 protein tests in April.
The study they could explain many of the problems from Covid-19. Raber stated in their experiments that transport of S1 was faster in the olfactory bulb and kidney of males than females.
This observation may be related to increased male vulnerability to more robust Covid-19 products.