Cancer is one of the most pressing health care problems in the world. The development of therapeutic agents with highly selective anti-cancer actions is becoming increasingly attractive due to the lack of tumor selection of conventional therapies.
Scientists at the Japan Advanced Institute of Science and Technology (JAIST) have created bacteria-based cancer optotheranostics.
Discovered by Professional Professor Eijiro Miyako and his team from JAIST, natural purple photosynthetic bacteria (PPSB) can play a key role as a highly active cancer immunotheranostics agent that utilizes the near and I biotechnical light I and II. on infrared (NIR) thanks. to the light-duty nanocomplexes in a microbial membrane. The NIR light-guided PPSB would be an effective “all-in-one” theoretical material for use in deep tumor treatment.
At the very least, the current work has the following major advantages compared to other cancer therapies such as anticancer drugs, nanomedicine, antibody, and conventional microbial therapies. 1) PPSB has high tumor specificity and non-pathogenity; 2) Adequate active cell proliferation and multifactivity such as NIR-I-to-NIR-II (FL) fluorescence, photothermal conversion, reactive oxygen species (ROS) generation, and differential photoacoustic effects (PA), can be added. simultaneous expression using NIR light exposure without chemical actions and genetic manipulation; 3) Complex and expensive methods are not required for their production as they can be multiplied by simple cultivation in a cheap medium.
The current experiments deserve further consideration of this novel theranostic approach to the treatment of rescue cancers. The team believes that the improved technology would advance cancer treatment to create a more effective treatment.
Source:
Japan Advanced Institute of Science and Technology