A state-of-the-art dural puncture sealant reduces cerebrospinal fluid leakage

These leaks could cause strong headaches that can last for weeks, delay recovery after intervention with this anesthetic method or make it more difficult for the mother to care for her. given to her baby after childbirth by epidural.

Epidural anesthesia is a technique that requires extreme precision to avoid the undiagnosed duodenum, one of the three meninx that protects the central nervous system. The cerebrospinal fluid, which feeds the nervous system, is located beneath the dura mater. Leaps of this stream can cause potentially severe strong headaches and delay the onset of intervention with this anesthetic method. They are especially severe in women who suffer from this problem after receiving an epidural during childbirth.

Valencian researcher Carlos García Victoria has patented a device that reduces cerebrospinal leakage if it inadvertently punishes the dura mater. It has been successfully tested in a lamb model, a necessary pre-emergence step for human intervention, performed at a Clinical Hospital of Medicine by lecturers from the Department of Medicine and Veterinary Surgery of the Faculty of Medicine and the Clinical Hospital of Veterinary Medicine. CEU Cardenal Herrera University (CEU UCH) José Ignacio Redondo, Mireia García Roselló, Álvaro Gutiérrez and Vicente Esteve.

Researchers from a number of institutions and universities have been involved in the design and creation of this innovative design. Carles García Vitoria, who performs his research duties at the Fisabio base, has been included by the American MIT on the ‘Innovators Under 35 Europe 2017’ list.

Dr. Miguel Ángel Reina, one of the world’s leading experts on dura mater injuries, is an expert from the Department of Anaesthesiology of the University of Florida, USA, CEU University of San Pablo and Montepríncipe Hospital. José de Andrés, member of the Department of Anesthesiology of the University of Valencia and General Hospital; and Andre Boezaart, from the University of Florida and the Alon P Winnie Research Institute in the Republic of South Africa.

The designed device can be applied immediately after detecting an accidental puncture of the dura mater, sealing the cerebrospinal leak in a simple manner. This avoids the reason why the scientific community connects with the subsequent headaches, which last several days or even weeks, extend hospital stays and recover from the intervention.

Step by step for human use

The results of its efficacy on an animal model were published in the journal with the second most influential journal on Human Anaesthesiology Internationally: Regional Anesthesia and Pain Medicine.

The design of this animal model has made it possible to successfully test the efficiency of the device. This is the essential first step in its use of empowerment. ”

José Ignacio Redondo, Lecturer in Anesthesiology, Faculty of Medicine, CEU UCH

Furthermore, the work of the multidisciplinary team of Human Medicine and Medicine “is a good example of the collaborative opportunities that professionals in one field and another need to achieve advances in anesthesia that are beneficial to humans and animals. ”