A study published in Nature Medicine shows that diets rich in plant-based foods power the presence of gut microorganisms associated with a lower risk of chronic diseases leading to -introduction of coronary heart disease.
The study was led by researchers from King’s College London, Massachusetts General Hospital (MGH), Harvard TH Chan School of Public Health, University of Trento, Italy, and startup health company ZOE.
A worldwide study using metagenomics and blood fertilizer profile has revealed a table of 15 gut microorganisms associated with lower risks in normal conditions, for example, corpulence and diabetes. type 2.
PREDICT 1 (Personal Responses to Divinity Compression Test 1) analyzed detailed data on the composition of gut microorganisms, their dietary habits, and cardiometabolic blood biomarkers. He found strong links between a person’s diet, the microbes in their gut (microbiome) and their health.
Researchers identified microbes that link ‘good’ or ‘bad’ and ‘bad’ with an individual’s risk of certain serious illnesses such as diabetes, heart disease and obesity. Surprisingly, the microbome is more closely related to these signals than other factors, such as genetics. Some of the identified microbes are so new that they have not yet been identified.
The researchers described a “healthy” diet as one in which a combination of foods was associated with a lower risk of chronic illness. They found that test subjects who ate such a diet, or one that was rich in plants, were more likely to be associated with high levels of ‘good’ gut microbes associated with a lower risk of common diseases.
The researchers also found microbiome-based biomarkers of obesity as well as indications for cardiovascular disease and glucose intolerance, which are key risk factors for COVID. These decisions can be used to help create personalized eating plans specifically designed to improve a person’s health.
“As a nutritionist, the discovery of novel microbes linked to specific foods, as well as metabolic health, is inspiring. Because of the highly personalized representation of midges each individual, our research is suggesting that we may be able to change our gut midges, and improve our health by choosing the best foods for our particular biology, “said Dr Sarah Berry, Reader in Nutritional Sciences at King ‘s College London.
For example, the findings suggest that mosquitoes rich in Prevotella copri and Blastocystis species were associated with maintaining a favorable blood sugar level after meals. Other species were associated with lower blood fat levels and symptoms of inflammation.
“When you eat, you’re not just nourishing your body, you’re feeding the trillions of microbes that live inside your gut,” said Dr Tim Spector, Epidemiologist from King’s College London, which started the PREDICT study program and is the scientific founder of ZO, said.
“We were surprised to see such large, clear groups of what we informally call ‘good’ and ‘bad’ microbes emerging from our analysis. It is also interesting to see that microbes know Biologists are so small about many of these microbes that they have not even been named yet, “said Nicola Segata, PhD, professor and principal investigator of the Computational Metagenomics Lab at the University of Trento, Italy and director of microbiome analysis study.
“This is now a major focus area for us, as we believe they could open up new perspectives in the future on how we can use the gut midge as a changing target for metabolism and human health. improve it, “Segata said.
PREDICT is the largest in-depth nutrition study in the world. PREDICT 1 was an international collaboration to study links between diet, the midges, and cardiometabolic health biomarkers. The researchers collected microbiome series data, detailed information on long-term diet, and results of hundreds of cardiometabolic blood markers from just over 1,100 participants in the US and UK. PREDICT 2 completed their main studies in 2020 with another 1,000 participants in the US, and PREDICT 3 launched a few months ago.
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This story was published from a wire group group with no text changes.
